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Mechanics of Biomaterials
Fundamental Principles for Implant Design

$122.00 (P)

Part of Cambridge Texts in Biomedical Engineering

  • Date Published: December 2011
  • availability: Available
  • format: Hardback
  • isbn: 9780521762212

$ 122.00 (P)

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About the Authors
  • Teaching mechanical and structural biomaterials concepts for successful medical implant design, this self-contained text provides a complete grounding for students and newcomers to the field. Split into three sections: Materials, Mechanics and Case Studies, it begins with a review of sterilization, biocompatibility and foreign body response before presenting the fundamental structures of synthetic biomaterials and natural tissues. Mechanical behavior of materials is then discussed in depth, covering elastic deformation, viscoelasticity and time-dependent behavior, multiaxial loading and complex stress states, yielding and failure theories, and fracture mechanics. The final section on clinical aspects of medical devices provides crucial information on FDA regulatory issues and presents case studies in four key clinical areas: orthopedics, cardiovascular devices, dentistry and soft tissue implants. Each chapter ends with a list of topical questions, making this an ideal course textbook for senior undergraduate and graduate students, and also a self-study tool for engineers, scientists and clinicians.

    • Teaches mechanical and structural biomaterial concepts for successful implant design
    • Includes step-by-step design guidelines throughout, enabling readers to understand how multiple aspects of failure can be evaluated for a material or device
    • Contains medical device case studies (orthopedic, cardiovascular, dental, soft tissue), which give the reader an in-depth view of implant evolution and design issues in four key clinical areas
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    Reviews & endorsements

    "Mechanics of Biomaterials is the textbook I have been waiting for. This comprehensive work synthesizes the science and engineering of biomaterials that has developed over the past three decades into a highly useful textbook for training students in two of the senior undergraduate/first-year graduate student courses I teach: Advanced Biomechanics, and Biomaterials and Medical Devices. In fact, as I reviewed this work it felt like I was reviewing my own lecture notes developed over 20 years. The work combines materials science, mechanics and medical device design and analysis in a seamless and thorough manner incorporating many critical studies from the literature into a clear and comprehensive work. Pruitt and Chakravartula have succeeded in developing an outstanding text and reference book that should be required reading for all who aspire to design, develop and evaluate medical devices." Jeremy L. Gilbert, Syracuse University

    "The authors have written a detailed yet easy-to-read book that can be used by materials scientists and biomedical engineers, from both the budding biomedical engineering student to the seasoned medical device designer. It combines the fundamentals of plastics, metals, and ceramics behavior with the required properties for the often challenging loading and environmental conditions found in the body. I particularly liked Pruitt and Chakravartula's technique of introducing a detailed discussion of the theoretical explanation of a particular material class's response to a loading environment, and then providing a real-life case study demonstrating how the theoretical response translates to clinical performance. The book is rich in practical examples of biomaterials used in permanent implants currently on the market. Sufficient historical information is provided on implant successes and failures to appreciate the challenges for material and design selection in the areas of both hard and soft tissue replacement." Stephen Spiegelberg, Cambridge Polymer Group, Inc., MA, USA

    "Mechanics of Biomaterials: Fundamental Principles for Implant Design provides a much needed comprehensive resource for engineers, physicians, and implant designers at every level of training and practice. The book includes a historical background which outlines the engineering basis of traditional implant designs, and interactions of materials, biology, and mechanics resulting in clinical success or failure of these devices. Each chapter contains a detailed description of the engineering principles which are critical to understand the mechanical behavior of biomaterials and implants in vivo. The scope of the text covers orthopaedics, cardiovascular devices, dental, and soft tissue implants, and should help considerably in our efforts to improve the function and durability of biomaterials and implants used in clinical practice." Michael Ries, University of California, San Francisco

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    Product details

    • Date Published: December 2011
    • format: Hardback
    • isbn: 9780521762212
    • length: 698 pages
    • dimensions: 254 x 203 x 38 mm
    • weight: 1.62kg
    • contains: 375 b/w illus. 35 tables 115 exercises
    • availability: Available
  • Table of Contents

    Part I. Materials:
    1. Biocompatibility, sterilization and materials selection for implant design
    2. Metals for medical implants
    3. Ceramics
    4. Polymers
    5. Mechanical behavior of structural tissues
    Part II. Mechanics:
    6. Elasticity
    7. Viscoelasticity
    8. Failure theories
    9. Fracture mechanics
    10. Fatigue
    11. Friction, lubrication and wear
    Part III. Case Studies:
    12. Regulatory affairs and testing
    13. Orthopedics
    14. Cardiovascular devices
    15. Oral and maxillofacial devices
    16. Soft tissue replacements
    Appendix A. Selected topics from mechanics of materials
    Appendix B. Table of material properties of engineering biomaterials and tissues
    Appendix C. Teaching methodologies in biomaterials
    List of symbols.

  • Resources for

    Mechanics of Biomaterials

    Lisa A. Pruitt, Ayyana M. Chakravartula

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  • Instructors have used or reviewed this title for the following courses

    • Advanced Biomaterials
    • Biomaterials
    • Biosolids
    • Introduction to Biomaterials
    • Materials in Medicine
  • Authors

    Lisa A. Pruitt, University of California, Berkeley
    Lisa A. Pruitt is the Lawrence Talbot Chair of Engineering at the University of California, Berkeley and also serves as an adjunct professor in the Department of Orthopedic Surgery at the University of California, San Francisco. She recently served as the Associate Dean of Lifelong Learning and Outreach Education in the College of Engineering and has received numerous awards including the Presidential Award for Excellence in Science, Mathematics and Engineering Mentoring (2004) and the Graduate Student Instructor Mentor Award from the University of California, Berkeley (2009).

    Ayyana M. Chakravartula, Exponent, Inc., Menlo Park, California
    Ayyana M. Chakravartula received her Ph.D. in Mechanical Engineering from the University of California, Berkeley in 2005. She currently works at Exponent, Inc. in Menlo Park, CA, in its Mechanics and Materials practice. She has worked as a research scientist at the Cambridge Polymer Group in Boston, MA, and has served as an adjunct lecturer at Boston University. She has mentored numerous students, interns and research assistants in her graduate and postgraduate career.

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