This concise overview of the fundamental concepts of cancer biology is ideal for those with little or no background in the field. A summary of global cancer patterns introduces students to the general principles of how cancers arise and the risk factors involved. By focusing on fundamental examples of the signalling pathways within cells, the functional effects of DNA damage are explained. Later chapters then build on this foundation to provide a comprehensive summary of the major signalling pathways that affect tumour development. Current therapeutic strategies are reviewed, along with a discussion of methods for tumour detection and biomarker identification. Finally, the impact of whole genome sequencing is discussed, bringing students up to date with key recent developments in the field. From basic principles to insights into cutting-edge research, this book will enable the reader to move into the cancer field with confidence.Read more
- Concise overview of the current picture of cancer biology for students with little or no background knowledge of the field
- Provides a unique summary of the ten major cancers, from risk factors and gene mutations to symptoms and treatments
- Explains the relevance of recent progress in genomics and proteomics for cancer treatment and diagnostics
Reviews & endorsements
"Cancer biology and cancer medicine are broad and extensive fields with fast moving research developing new knowledge of many aspects of cancer. Modern technologies are increasing the pace of acquisition of new knowledge and contributing to real progress in managing patients.
Robin Hesketh has produced a remarkable Introduction to Cancer Biology which covers all of the key areas of current knowledge and brings them up to date with current research concepts and developments. He writes in an accessible way that will be valuable for students fresh to biology but also produces a book that will be very useful to experienced biologists and physicians who want to have to hand a broad overview of this fast moving and diverse field.
The structure of the book is clear and informative and encompasses critically important biological knowledge from the level of the cell to population studies in epidemiology. The appendices are very useful providing ready access to information on most common cancer and most of the major tabulations of existing knowledge that we may need.
In the era of internet access and publication databases, it is very challenging to introduce a book which is really useful both for new students and established practitioners. Robin Hesketh has succeeded remarkably well in doing so."
Professor Peter Selby, Director of the Leeds Institute of Molecular MedicineSee more reviews
"The structure of the book is clear and well organized. The author writes well, giving excellent explanations of concepts ranging from basic principles to cutting-edge research. The book is a valuable resource for introducing lower-level students to the biology of cancer. Highly recommended."
H. Zhou, Seton Hall University for Choice Magazine
Review was not posted due to profanity×
- Date Published: January 2013
- format: Paperback
- isbn: 9781107601482
- length: 352 pages
- dimensions: 246 x 189 x 18 mm
- weight: 0.8kg
- contains: 130 b/w illus. 38 colour illus.
- availability: Temporarily unavailable - available from July 2019
Table of Contents
1. Lessons from epidemiology
2. Causes of cancer
3. Signalling in normal cells
4. 'Cancer genes': mutations and cancer development
5. What is a tumour?
6. Cancer signalling networks
7. The future of cancer prevention, diagnosis and treatment
8. The future of cancer in the post-genomic era
Ten major cancers at a glance
Appendix. Targets of specific anti-cancer drugs
Find resources associated with this titleYour search for '' returned .
Type Name Unlocked * Format Size
*This title has one or more locked files and access is given only to instructors adopting the textbook for their class. We need to enforce this strictly so that solutions are not made available to students. To gain access to locked resources you either need first to sign in or register for an account.
These resources are provided free of charge by Cambridge University Press with permission of the author of the corresponding work, but are subject to copyright. You are permitted to view, print and download these resources for your own personal use only, provided any copyright lines on the resources are not removed or altered in any way. Any other use, including but not limited to distribution of the resources in modified form, or via electronic or other media, is strictly prohibited unless you have permission from the author of the corresponding work and provided you give appropriate acknowledgement of the source.
If you are having problems accessing these resources please email firstname.lastname@example.org
Sorry, this resource is locked
Please register or sign in to request access. If you are having problems accessing these resources please email email@example.comRegister Sign in
You are now leaving the Cambridge University Press website. Your eBook purchase and download will be completed by our partner www.ebooks.com. Please see the permission section of the www.ebooks.com catalogue page for details of the print & copy limits on our eBooks.Continue ×