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Adaptive Dynamics of Infectious Diseases
In Pursuit of Virulence Management

$66.00 ( ) USD

Part of Cambridge Studies in Adaptive Dynamics

Karl Sigmund, Maurice W. Sabelis, Ulf Dieckmann, J. A. J. Metz, Paul W. Ewald, Guilio De Leo, Andy Dobson, Andy Goodman, Minus van Baalen, Greg Dwyer, Jonathan Dushoff, Joseph S. Elkinton, John P. Burand, Simon A. Levin, Robert D. Holt, Michael E. Hochberg, Martin A. Nowak, Frederick R. Adler, Julio Mosquero Losada, Sylvain Gandon, Yannis Michalakis, Andrew F. Read, Margaret J. Mackinnon, M. Ali Anwar, Louise H. Taylor, David C. Krakauer, Joost B. Beltman, José A. M. Borghans, Rob J. de Boer, Viggo Andreasen, Akira Sasaki, Claus Wedekind, Bruce Rannala, Rolf F. Hoekstra, Alfons J. M. Debets, Douglas R. Taylor, Bas Pels, Martijn Egas, Arne Janssen, Sebastian Bonhoeffer, Angela R. McLean, Sunetra Gupta, Marc Lipsitch, Mart C. M. de Jong, Luc L. G. Janss, Andrew Jarosz, Sam L. Elliot
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  • Date Published: January 2011
  • availability: This ISBN is for an eBook version which is distributed on our behalf by a third party.
  • format: Adobe eBook Reader
  • isbn: 9780511825958

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About the Authors
  • This monograph takes stock of our current knowledge on the evolutionary ecology of infectious diseases, and sets out the goals for the management of virulent pathogens. Throughout the text, the fundamental concepts and techniques underlying the models are carefully explained in a unique series of integrated boxes.

    • First book to integrate mathematical evolutionary modelling and disease management
    • Contains integrated boxes to review fundamental concepts and techniques behind the modeling
    • Presents novel approaches to the evolutionary management of disease virulence
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    Reviews & endorsements

    "The volume achieves its aims of being an introductory text for researchers to expand their range of knowledge and stimulate new enquiry." Dr. Jodie McVernon, Epidemiol Infect

    "Virulence management will continue to be a hot topic that will undoubtedly be subject to much refinement. This book provides an outstanding treatment of the ecological, evolutionary, and physiological richness of this active area of research. Ecologists will find it richly rewarding and stimulating, and if health professionals give it a try, they will find much to guide health policy." Ecoscience

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    Product details

    • Date Published: January 2011
    • format: Adobe eBook Reader
    • isbn: 9780511825958
    • contains: 118 b/w illus. 12 tables
    • availability: This ISBN is for an eBook version which is distributed on our behalf by a third party.
  • Table of Contents

    1. Introduction Karl Sigmund, Maurice W. Sabelis, Ulf Dieckmann and J. A. J. Metz
    Part I. Setting the Stage:
    2. Alternative transmission modes and the evolution of virulence Paul W. Ewald and Guilio De Leo
    3. Wildlife perspectives on the evolution of virulence Guilio De Leo, Andy Dobson and Andy Goodman
    4. Adaptive dynamics of pathogen-host interactions Ulf Dieckmann
    5. Dilemmas in virulence management Minus van Baalen
    Part II. Host Population Structure:
    6. Variation in susceptibility: lessons from an insect virus Greg Dwyer, Jonathan Dushoff, Joseph S. Elkinton, John P. Burand and Simon A. Levin
    7. Contact networks and the evolution of virulence Minus van Baalen
    8. Virulence on the edge: a source-sink perspective Robert D. Holt and Michael E. Hochberg
    Part III. Within-Host Interactions:
    9. Super- and coinfection: the two extremes Martin Nowak and Karl Sigmund
    10. Super- and coinfection: filling the range Frederick Adler and Julio Mosquero Losada
    11. Multiple infection and its consequences for virulence management Sylvain Gandon and Yannis Michalakis
    12. Kin selection models as evolutionary explanations of malaria Andrew F. Read, Margaret J. Mackinnon, M. Ali Anwar and Louise H. Taylor
    Part IV. Pathogen-Host Coevolution:
    13. Coevolution of virus and host cell death signals David C. Krakauer
    14. Biogeographical perspectives on arms races Michael E. Hochberg and Robert D. Holt
    15. Major histocompatability complex: polymorphism from coevolution Joost B. Beltman, José A. M. Borghans and Rob J. de Boer
    16. Virulence management and disease resistance in diploid hosts Viggo Andreasen
    17. Coevolution in gene-for-gene systems Akira Sasaki
    18. Implications of sexual selection for virulence management Claus Wedekind
    19. Molecular phylogenies and virulence evolution Bruce Rannala
    Part V. Multilevel Selection:
    20. Weakened from within: intragenomic conflict and virulence Rolf F. Hoekstra and Alfons J. M. Debets
    21. Ecology and evolution of chestnut blight fungus Douglas R. Taylor
    22. Evolution of exploitation and defense in tritrophic interactions Maurice W. Sabelis, Minus van Baalen, Bas Pels, Martijn Egas and Arne Janssen
    Part VI. Vaccines and Drugs:
    23. Managing antibiotic resistance Sebastian Bonhoeffer
    24. Evolution of vaccine-resistant strains of infectious agents Angela McLean
    25. Pathogen evolution: the case of malaria Sunetra Gupta
    26. Vaccination and serotype replacement Marc Lipsitch
    Part VII. Perspectives for Virulence Management:
    27. Taking stock: relating theory to experiment Maurice W. Sabelis and Johan A. J. Metz
    28. Virulence management in humans Paul W. Ewald
    29. Virulence management in wildlife populations Guilio De Leo and Andy Dobson
    30. Virulence management in veterinary epidemiology Mart C. M. de Jong and Luc L. G. Janss
    31. Virulence management in plant-pathogen interactions Andrew M. Jarosz
    32. Management of virulence in biocontrol agents Sam L. Elliot, Maurice W. Sabelis and Frederick R. Adler
    33. Epilogue Ulf Dieckmann, Karl Sigmund, Maurice W. Sabelis and Johan A. J. Metz.

  • Editors

    Ulf Dieckmann, International Institute for Applied Systems Analysis, Austria
    Ulf Dieckmann is Project Coordinator of the Adaptive Dynamics Network at the International Institute for Applied Systems Analysis (IIASA) in Laxenburg, Austria. He is coeditor of The Geometry of Ecological Interactions.

    Johan A. J. Metz, Universiteit Leiden
    J. (Hans) A. J. Metz is Professor of Mathematical Biology at the Institute of Evolutionary and Ecological Sciences at the University of Leiden, and Project Leader of the Adaptive Dynamics Network at IIASA. He is coeditor of The Geometry of Ecological Interactions.

    Maurice W. Sabelis, Universiteit van Amsterdam
    Maurice W. Sabelis is at the Institute for Biodiversity and Ecosystem Dynamics at the University of Amsterdam.

    Karl Sigmund, Universität Wien, Austria
    Karl Sigmund is Professor at the Institute for Mathematics at the University of Vienna and also a Research Associate with the Adaptive Dynamics Network at IIASA. He is coauthor of Evolutionary Games and Population Dynamics.

    Contributors

    Karl Sigmund, Maurice W. Sabelis, Ulf Dieckmann, J. A. J. Metz, Paul W. Ewald, Guilio De Leo, Andy Dobson, Andy Goodman, Minus van Baalen, Greg Dwyer, Jonathan Dushoff, Joseph S. Elkinton, John P. Burand, Simon A. Levin, Robert D. Holt, Michael E. Hochberg, Martin A. Nowak, Frederick R. Adler, Julio Mosquero Losada, Sylvain Gandon, Yannis Michalakis, Andrew F. Read, Margaret J. Mackinnon, M. Ali Anwar, Louise H. Taylor, David C. Krakauer, Joost B. Beltman, José A. M. Borghans, Rob J. de Boer, Viggo Andreasen, Akira Sasaki, Claus Wedekind, Bruce Rannala, Rolf F. Hoekstra, Alfons J. M. Debets, Douglas R. Taylor, Bas Pels, Martijn Egas, Arne Janssen, Sebastian Bonhoeffer, Angela R. McLean, Sunetra Gupta, Marc Lipsitch, Mart C. M. de Jong, Luc L. G. Janss, Andrew Jarosz, Sam L. Elliot

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