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Fundamentals of Inflammation

$145.00 (P)

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Peter Ward, Derek W. Gilroy, Christopher L. Karp, Jose U. Scher, Steven B. Abramson, Michael H. Pillinger, Marco A. Cassatella, Joshua A. Boyce, Jonathan Arm, David Sloane, Sophie Fillon, Steven J. Ackerman, Glenn T. Furuta, Sarah Fox, Adriano G. Rossi, Tracy Hussell, Andrew Filer, Christopher D. Buckley, János G. Filep, Sean Colgan, Charles Serhan, Jesper Z. Haeggström, Nick Lukacs, György Haskó, Bruce Cronstein, William Nauseef, Lucy V. Norling, Giovanni Leoni, Dianne Cooper, Mauro Perretti, Tony L. Yaksh, Roderick Flower, Samir S. Ayoub, Thorsten Hagemann, Toby Lawrence, Bruce D. Levy, Andrew P. Lieberman, Constance D'Amato, Caroline Gordon, Linda Vong, Paul L. Beck, John Wallace, Gayathri K. Perera, Frank Nestle, Jeremy Duffield, Joel Henderson, Kenneth K. Wu, André L. F. Sampaio, Neil Dufton, Aidan Ryan, Denise M. Sadlier, Catherine Godson, Jeremy Duffield, Bruce D. Levy, Mike Seed, Karsten Gronert, Aksam Merched, Lawrence Chan, Alpdogan Kantarci, Hatice Hasturk, Thomas E. Van Dyke, Fabiana S. Machado, Julio Aliberti, Michael J. Clare-Salzler
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  • Date Published: April 2010
  • availability: In stock
  • format: Hardback
  • isbn: 9780521887298

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  • The acute inflammatory response is the body’s first system of alarm signals that are directed toward containment and elimination of microbial invaders. Uncontrolled inflammation has emerged as a pathophysiologic basis for many widely occurring diseases in the general population that were not initially known to be linked to the inflammatory response, including cardiovascular disease, asthma, arthritis, and cancer. To better manage treatment, diagnosis, and prevention of these wide-ranging diseases, multidisciplinary research efforts are underway in both academic and industry settings. The purpose of this book is to provide an introduction to the cell types, chemical mediators, and general mechanisms of the host’s first response to invasion. World-class experts from institutions around the world have written chapters for this introductory text. The text is presented as an introductory springboard for graduate students, postdoctoral Fellows, medical scientists, and researchers from other disciplines who wish to gain an appreciation and working knowledge of current cellular and molecular mechanisms fundamental to inflammation.

    • First introductory textbook on subject of inflammation
    • Divided into six sections covering all basic aspects of inflammation, from cell types to cutting-edge animal models
    • Contributions by leading researchers around the world on the inflammatory response
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    Reviews & endorsements

    "A comprehensive volume that brings together many important and contemporary aspects of inflammation. The book will serve as an excellent guide to the current understanding of how "inflammation" contributes in such diverse ways to disease processes, and to the resolution of the same through natural processes or clinical treatment."
    Andrew Mellor, Quarterly Review of Biology

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    Product details

    • Date Published: April 2010
    • format: Hardback
    • isbn: 9780521887298
    • length: 488 pages
    • dimensions: 286 x 220 x 26 mm
    • weight: 1.61kg
    • contains: 99 b/w illus. 44 tables
    • availability: In stock
  • Table of Contents

    Part I:
    1. Acute inflammation and chronic inflammation Peter Ward
    2. Resolution of acute inflammation and wound healing Derek W. Gilroy
    3. Links between innate and adaptive immunity Christopher L. Karp
    Part II. Individual Cell Types:
    4A. Neutrophils I Jose U. Scher, Steven B. Abramson and Michael H. Pillinger
    4B. Neutrophils II Marco A. Cassatella
    5. Mast cells as sentinels of inflammation Joshua A. Boyce
    6. Basophils Jonathan Arm and David Sloane
    7. Eosinophils Sophie Fillon, Steven J. Ackerman and Glenn T. Furuta
    8. Macrophages Sarah Fox and Adriano G. Rossi
    9. Lymphocytes Tracy Hussell
    10. Fibroblasts and stromal cells Andrew Filer and Christopher D. Buckley
    11. Cell-cell interactions: PMN endothelial cells János G. Filep and Sean Colgan
    Part III. Chemical Mediators:
    12. Lipid mediators in acute inflammation and resolution: eicosanoids, PAF, resolvins and protectins Charles Serhan and Jesper Z. Haeggström
    13. Cytokines and chemokines / IL-1 family in inflammation Nick Lukacs
    14. Adenosine receptors: therapeutic aspects for inflammatory and immune diseases György Haskó and Bruce Cronstein
    15. Leukocyte generation of reactive oxygen species William Nauseef
    16. Cell adhesion molecules Lucy V. Norling, Giovanni Leoni, Dianne Cooper and Mauro Perretti
    Part IV. Immunopharmacology:
    17. Mediators and mechanisms of inflammatory pain Tony L. Yaksh
    18. Non-steroidal anti-inflammatory drugs Roderick Flower and Samir S. Ayoub
    19. Cytokines and chemokines in inflammation cancer Thorsten Hagemann and Toby Lawrence
    Part V. Inflammatory Diseases/Histology:
    20. Lung Bruce D. Levy
    21. Neural inflammation, Alzheimer's disease and stroke Andrew P. Lieberman and Constance D'Amato
    22. Rheumatoid arthritis/SLE Karim Raza and Caroline Gordon
    23. Gastrointestinal inflammation and ulceration: mediators of induction and resolution Linda Vong, Paul L. Beck and John Wallace
    24. Inflammatory skin diseases Gayathri K. Perera and Frank Nestle
    25. Kidney glomerulonephritis and renal ischemia Jeremy Duffield and Joel Henderson
    26. Inflammation in cardiovascular diseases Kenneth K. Wu
    Part VI. Animal Models of Inflammation:
    27. Models of acute inflammation – air-pouch, peritonitis and ischemia-reperfusion André L. F. Sampaio, Neil Dufton and Mauro Perretti
    28A. Experimental models of glomerulonephritis Aidan Ryan, Denise M. Sadlier and Catherine Godson
    28B. Ischemia reperfusion injury and glomerulonephritis Jeremy Duffield
    29. Asthma Bruce D. Levy
    30. Arthritis Mike Seed
    31. Ocular inflammation models Karsten Gronert
    32. Atherosclerosis in experimental animal models Aksam Merched and Lawrence Chan
    33. Oral inflammation and periodontitis Alpdogan Kantarci, Hatice Hasturk and Thomas E. Van Dyke
    34. Pathogens and inflammation Fabiana S. Machado and Julio Aliberti
    35. Diabetes Michael J. Clare-Salzler.

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    Fundamentals of Inflammation

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  • Editors

    Charles N. Serhan, Harvard Medical School
    Charles N. Serhan, PhD, is the Simon Gelman Professor of Anesthesia at Brigham and Women's Hospital, Director of the Center for Experimental Therapeutics and Reperfusion Injury, and Professor of Biochemistry and Molecular Pharmacology at Harvard Medical School, Cambridge, Massachusetts. He is one of the world's top researchers on inflammation and mediation.

    Peter A. Ward, University of Michigan, Ann Arbor
    Peter A. Ward, MD, is Stobbe Professor of Pathology at the University of Michigan Health Systems, Ann Arbor, Michigan. Dr Ward is past President of the United States and Canadian Academy of Pathology.

    Derek W. Gilroy, University College London
    Derek W. Gilroy, PhD, is a lecturer in the Centre for Clinical Pharmacology, University College London, United Kingdom. He has received the Bayer Aspirin Prize and is a Wellcome Trust Research Career Development Fellow.

    With contributions by

    Samir S. Ayoub

    Contributors

    Peter Ward, Derek W. Gilroy, Christopher L. Karp, Jose U. Scher, Steven B. Abramson, Michael H. Pillinger, Marco A. Cassatella, Joshua A. Boyce, Jonathan Arm, David Sloane, Sophie Fillon, Steven J. Ackerman, Glenn T. Furuta, Sarah Fox, Adriano G. Rossi, Tracy Hussell, Andrew Filer, Christopher D. Buckley, János G. Filep, Sean Colgan, Charles Serhan, Jesper Z. Haeggström, Nick Lukacs, György Haskó, Bruce Cronstein, William Nauseef, Lucy V. Norling, Giovanni Leoni, Dianne Cooper, Mauro Perretti, Tony L. Yaksh, Roderick Flower, Samir S. Ayoub, Thorsten Hagemann, Toby Lawrence, Bruce D. Levy, Andrew P. Lieberman, Constance D'Amato, Caroline Gordon, Linda Vong, Paul L. Beck, John Wallace, Gayathri K. Perera, Frank Nestle, Jeremy Duffield, Joel Henderson, Kenneth K. Wu, André L. F. Sampaio, Neil Dufton, Aidan Ryan, Denise M. Sadlier, Catherine Godson, Jeremy Duffield, Bruce D. Levy, Mike Seed, Karsten Gronert, Aksam Merched, Lawrence Chan, Alpdogan Kantarci, Hatice Hasturk, Thomas E. Van Dyke, Fabiana S. Machado, Julio Aliberti, Michael J. Clare-Salzler

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