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Mammalian Host Defense Peptides

Mammalian Host Defense Peptides

$185.00 (C)

Part of Advances in Molecular and Cellular Microbiology

R. I. Lehrer, D. A. Devine, D. Yang, J. J. Oppenheim, T. J. Falla, L. Zhang, G. Diamond, D. Laube, M. Klein-Patel, G. Gudmundsson, B. Agerberth, C. Bevins, T. Ganz, K. A. Brogden, M. Ackermann, J. Zabner, M. J. Welsh, R. E. W. Hancock, E. J. Helmerhorst, F. G. Oppenheim, M. R. Yeaman, R. Tamayo, A. C. Portillo, J. S. Gunn, R. Bals
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  • Date Published: September 2004
  • availability: In stock
  • format: Hardback
  • isbn: 9780521822206

$ 185.00 (C)
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About the Authors
  • This book draws together contributions from many leading scientists and reviews the most significant recent advances in the development of mammalian host defense peptides. These short, cationic single gene products have been isolated from a vast array of higher and lower organisms, and the conservation of function across so many species is an indication of their importance. Antimicrobial peptides are also the only new class of antimicrobial agent discovered in recent years, and there is interest in them as alternatives to conventional antibiotics.

    • The only currently available volume that deals specifically with mammalian antimicrobial peptides
    • Provides a unique multi-disciplinary approach, covering the biology and expression of these peptides, as well as their roles in health and disease
    • Written by leading experts in the field to provide an up-to-the minute overview of the topic at the molecular level
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    Product details

    • Date Published: September 2004
    • format: Hardback
    • isbn: 9780521822206
    • length: 408 pages
    • dimensions: 237 x 157 x 28 mm
    • weight: 0.776kg
    • contains: 20 b/w illus. 4 colour illus. 9 tables
    • availability: In stock
  • Table of Contents

    1. Overview: antimicrobial peptides, as seen from a rear-view mirror R. I. Lehrer
    2. Cationic antimicrobial peptides in regulation of commensal and pathogenic microbial populations D. A. Devine
    3. Multiple functions of antimicrobial peptides in host immunity D. Yang and J. J. Oppenheim
    4. Therapeutic potential and applications of innate immunity peptides T. J. Falla and L. Zhang
    5. Mammalian β−Defensins in mucosal defence G. Diamond, D. Laube and M. Klein-Patel
    6. Biology and expression of the human cathelicidin LL-37 G. Gudmundsson and B. Agerberth
    7. Antimicrobial peptides of the alimentary tract of mammals C. Bevins and T. Ganz
    8. Antimicrobial peptides suppress microbial infections and sepsis in animal models K. A. Brogden, M. Ackermann, J. Zabner and M. J. Welsh
    9. Bacterial structure and physiology: influence on susceptibility to antimicrobial peptides R. E. W. Hancock
    9. The antifungal mechanisms of antimicrobial peptides E. J. Helmerhorst and F. G. Oppenheim
    10. Antimicrobial peptides from platelets in defence against cardiovascular infections M. R. Yeaman
    11. Mechanisms of bacterial resistance to antimicrobial peptides R. Tamayo, A. C. Portillo and J. S. Gunn
    12. Roles of antimicrobial peptides in pulmonary disease R. Bals.

  • Editors

    Deirdre A. Devine, University of Leeds

    Robert E. W. Hancock, University of British Columbia, Vancouver

    Contributors

    R. I. Lehrer, D. A. Devine, D. Yang, J. J. Oppenheim, T. J. Falla, L. Zhang, G. Diamond, D. Laube, M. Klein-Patel, G. Gudmundsson, B. Agerberth, C. Bevins, T. Ganz, K. A. Brogden, M. Ackermann, J. Zabner, M. J. Welsh, R. E. W. Hancock, E. J. Helmerhorst, F. G. Oppenheim, M. R. Yeaman, R. Tamayo, A. C. Portillo, J. S. Gunn, R. Bals

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