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Biology and Pathology of the Oocyte

Biology and Pathology of the Oocyte
Its Role in Fertility and Reproductive Medicine

$247.00 (G)

Roger Short, Anne Grete Byskov, Majken Neilsen, Alain Gougeon, M. J. Faddy, Roger Gosden, Mary Bownes, Stephen Pathirana, Jurrien Dean, J. K. Findlay, V. Duranthon, J. P. Renard, Yanfeng Dai, Robert Moor, Josef Fulka Jr, A. Henry Sathananthan, Laura Hewitson, Joao Ramalho-Santos, Calvin Simerly, Gerald Schatten, Philippe Collas, Rafael Fissore, Jonathan Van Blerkom, Eric A. Shoubridge, Ursula Eichenlaub-Ritter, Gerard S. Conway, Sophie Christin-Maitre, John J. Eppig, Alan Trouson, Marc-André Sirard, Roger G. Gosden, J. M. Shaw
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  • Date Published: August 2003
  • availability: In stock
  • format: Hardback
  • isbn: 9780521799584

$ 247.00 (G)
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About the Authors
  • The human oocyte, or egg, is the rarest and most rapidly aging cell in the body, and is essential for fertility. This book is about the development and pathology of the oocyte, and includes information on new technologies to manipulate, enhance, and control fertility. Leading world experts contribute essays on the basic and applied science of the egg, its clinical manipulation, and its pivotal role in reproductive medicine and biology.

    • The oocyte is the rarest and most rapidly ageing cell in the body
    • The oocyte is the origin of chromosomal anomalies
    • The oocyte is a potential target for the contraception of the future
    • Roger Gosden is also well known as the author of Designer Babies
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    Reviews & endorsements

    "...authoritative...remarkable...fascinating..." G. Sacks, Journal of Obstetrics and Gynaecology

    "...just right...This book is a comprehensive, but easy to read, insight into current oocyte biology. As a satisfying review for the reproductive biologist, a scientific insight to the clinician or just an update on Eggbert this book hits the mark. It allows us to glimpse the future of reproductive biology and I recommend it highly." W. Colin Duncan, University of Edinburgh, The Obstetrician & Gynaecologist

    "...contains much useful information and covers the breadth of the field. For those who desire an introduction to the biology of the oocyte, it is an outstanding resource. For those who work with oocytes, the book will serve as an invaluable educational tool. I suspect there are very few readers who would not learn something valuable from this book." The New England Journal of Medicine

    "This book is... not only essential reading for all scientists and clinicians involved with infertility, it has a wider appeal to all specialists in reproductive medicine, animal breeding and even fetal development." Fertility & Sterility

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    Product details

    • Date Published: August 2003
    • format: Hardback
    • isbn: 9780521799584
    • length: 362 pages
    • dimensions: 256 x 195 x 24 mm
    • weight: 1.02kg
    • availability: In stock
  • Table of Contents

    Preface
    Part I. Historical Perspective:
    1. The magic and mystery of the oocyte: ex ovo omnia Roger Short
    Part II. Life Cycle:
    2. Ontogeny of the mammalian ovary Anne Grete Byskov and Majken Neilsen
    3. The early stages of follicle growth Alain Gougeon
    4. Modelling the dynamics of ovarian follicle utilisation throughout life M. J. Faddy and Roger Gosden
    5. Comparative aspects of oogenesis Mary Bownes and Stephen Pathirana
    Part III. Developmental Biology:
    6. Oocyte-specific gene expression: roles in folliculogenesis, fertilization and early development Jurrien Dean
    7. Morphology and pathology of the human oocyte A. Henry Sathananthan
    8. Storage and functional recovery of molecules in oocytes V. Duranthon and J. P. Renard
    9. Endocrine regulation of meiosis - local and systemic hormonal influences J. K. Findlay
    10. Checkpoint controls in mammalian oocytes Yanfeng Dai, Robert Moor and Josef Fulka Jr
    11. Fertilization: fate of sperm components after ICSI Laura Hewitson, Joao Ramalho-Santos, Calvin Simerly and Gerald Schatten
    12. Activation of the mammalian egg Philippe Collas and Rafael Fissore
    13. Clinical application of symmetry, asymmetry and polarity in early human development Jonathan Van Blerkom
    Part IV. Pathology:
    14. The legacy of mitochondrial DNA Eric A. Shoubridge
    15. Aneuploidy in ageing oocytes and after toxic insult Ursula Eichenlaub-Ritter
    16. Genetic basis of primary ovarian failure Gerard S. Conway and Sophie Christin-Maitre
    Part V. Technology and Clinical Medicine:
    17. Growth and development of the mammalian oocyte-granulosa cell complex in culture John J. Eppig
    18. Human oocyte maturation in vitro Alan Trouson
    19. Follicular factors affecting oocyte maturation and development competence Marc-André Sirard
    20. Low temperature storage of follicular and ovulated oocytes Roger G. Gosden
    21. Fecundity of transplanted ovaries J. M. Shaw
    Index.

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    Biology and Pathology of the Oocyte

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  • Editors

    Alan O. Trounson, Monash University, Victoria

    Roger G. Gosden, Eastern Virginia Medical School

    Contributors

    Roger Short, Anne Grete Byskov, Majken Neilsen, Alain Gougeon, M. J. Faddy, Roger Gosden, Mary Bownes, Stephen Pathirana, Jurrien Dean, J. K. Findlay, V. Duranthon, J. P. Renard, Yanfeng Dai, Robert Moor, Josef Fulka Jr, A. Henry Sathananthan, Laura Hewitson, Joao Ramalho-Santos, Calvin Simerly, Gerald Schatten, Philippe Collas, Rafael Fissore, Jonathan Van Blerkom, Eric A. Shoubridge, Ursula Eichenlaub-Ritter, Gerard S. Conway, Sophie Christin-Maitre, John J. Eppig, Alan Trouson, Marc-André Sirard, Roger G. Gosden, J. M. Shaw

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