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Integrative Mechanobiology
Micro- and Nano- Techniques in Cell Mechanobiology

CAD$176.95 (C)

Eddie Y. Chung, Qin Qin, Agamoni Bhattacharyya, Shaoying Lu, Yingxiao Wang, Niels Volkmann, Dorit Hanein, Yue Shao, Shinuo Weng, Jianping Fu, Christopher Moraes, Luke A. MacQueen, Yu Sun, Craig A. Simmons, Koichiro Uto, Elliot Fisher, Hong-Nam Kim, Chang Ho Seo, Deok-Ho Kim, Murat Guvendiren, Jason A. Burdick, Jiandong Wu, Francis Lin, Teresa Zulueta-Coarasa, Rodrigo Fernandez-Gonzalez, Ge Yang, Hao-Chih Lee, Yasaman Nematbakhsh, Chwee Teck Lim, Mitsuhiro Ebara, Andrew W. Holle, Jennifer L. Young, Yu Suk Choi, Chao Liu, Kevin Middleton, Lidan You, Vincent F. Fiore, Dwight M. Chambers, Thomas H. Barker, Andrea Leonard, Marita L. Rodriguez, Nathan J. Sniadecki, Hye Mi Kim, Junsang Doh, Yoojin Shin, Sewoon Han, Hyo-Eun Jeong, Jeong Ah Kim, Jessie S. Jeon, Sid Chung, Jerel Mueller, William Tyler
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  • Date Published: January 2016
  • availability: In stock
  • format: Hardback
  • isbn: 9781107078390

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About the Authors
  • The first of its kind, this comprehensive resource integrates cellular mechanobiology with micro-nano techniques to provide unrivalled in-depth coverage of the field, including state-of-the-art methods, recent advances, and biological discoveries. Structured in two parts, the first part offers detailed analysis of innovative micro-nano techniques including FRET imaging, electron cryo-microscopy, micropost arrays, nanotopography devices, laser ablation, and computational image analysis. The second part of the book provides valuable insights into the most recent technological advances and discoveries in areas such as stem cell, heart, bone, brain, tumor, and fibroblast mechanobiology. Written by a team of leading experts and well-recognised researchers, this is an essential resource for students and researchers in biomedical engineering.

    • Describes state-of-the-art techniques and introduces the most recent progress in the field
    • Written by a team of well-known researchers
    • The first work of its kind, combining cellular mechanobiology with micro-nano technologies
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    Product details

    • Date Published: January 2016
    • format: Hardback
    • isbn: 9781107078390
    • length: 382 pages
    • dimensions: 252 x 177 x 20 mm
    • weight: 0.9kg
    • contains: 89 b/w illus.
    • availability: In stock
  • Table of Contents

    Part I. Micro/Nano Techniques in Cell Mechanobiology:
    1. Nanotechnologies and FRET imaging in live cells Eddie Y. Chung, Qin Qin, Agamoni Bhattacharyya, Shaoying Lu and Yingxiao Wang
    2. Electron microscopy and three-dimensional single-particle analysis as tools for understanding the structural basis of mechanobiology Niels Volkmann and Dorit Hanein
    3. Stretchable micropost array cytometry: a powerful tool for cell mechanics and mechanobiology research Yue Shao, Shinuo Weng and Jianping Fu
    4. Microscale generation of dynamic forces in cell culture systems Christopher Moraes, Luke A. MacQueen, Yu Sun and Craig A. Simmons
    5. Multi-scale topographical approaches for cell mechanobiology studies Koichiro Uto, Elliot Fisher, Hong-Nam Kim, Chang Ho Seo and Deok-Ho Kim
    6. Hydrogels with dynamically tunable properties Murat Guvendiren and Jason A. Burdick
    7. Micro-engineered tools for studying cell migration in electric fields Jiandong Wu and Francis Lin
    8. Laser ablation to investigate cell and tissue mechanics in vivo Teresa Zulueta-Coarasa and Rodrigo Fernandez-Gonzalez
    9. Computational image analysis techniques for cell mechanobiology Ge Yang and Hao-Chih Lee
    10. Micro- and nanotools to probe cancer cell mechanics and mechanobiology Yasaman Nematbakhsh and Chwee Teck Lim
    11. Stimuli-responsive polymeric substrates for cell-matrix mechanobiology Mitsuhiro Ebara and Koichiro Uto
    Part II. Recent Progress in Cell Mechanobiology:
    12. Forces of nature: understanding the role of mechanotransduction in stem cell differentiation Andrew W. Holle, Jennifer L. Young and Yu Suk Choi
    13. Heart valve mechanobiology Craig Simmons
    14. Bone cell mechanobiology using micro- and nano-techniques Chao Liu, Kevin Middleton and Lidan You
    15. Molecular mechanisms of cellular mechanotransduction in wound healing Vincent F. Fiore, Dwight M. Chambers and Thomas H. Barker
    16. Micropost arrays as a means to assess cardiac muscle cells Andrea Leonard, Marita L. Rodriguez and Nathan J. Sniadecki
    17. Micro/nanofabrication for the study of biochemical and biomechanical regulation of T cell activation Hye Mi Kim and Junsang Doh
    18. Study of tumor angiogenesis using microfluidic approaches Yoojin Shin, Sewoon Han, Hyo-Eun Jeong, Jeong Ah Kim, Jessie S. Jeon and Sid Chung
    19. Neuromechanobiology of the brain: mechanics of neuronal structure, function, and pathophysiology Jerel Mueller and William Tyler.

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    Integrative Mechanobiology

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  • Editors

    Yu Sun, University of Toronto
    Yu Sun is a Professor at the University of Toronto with cross-appointments in the Department of Mechanical and Industrial Engineering, the Institute of Biomaterials and Biomedical Engineering, and the Department of Electrical and Computer Engineering. He is the Canada Research Chair in Micro- and Nano-Engineering Systems. He was inducted Fellow of ASME, IEEE, and CAE for his work on micro-nano devices and robotic systems. His awards include the 2010 IEEE Robotics and Automation Society Early Career Award and an NSERC E. W. R. Steacie Memorial Fellowship in 2013.

    Deok-Ho Kim, University of Washington
    Deok-Ho Kim is a Professor in the Department of Bioengineering at the University of Washington. His active research in the areas of micro/nanotechnologies, systems mechanobiology and tissue engineering has been recognized with many awards including the Samsung Humantech Thesis Award (2009), the Harold M. Weintraub Award in Biological Sciences (2010), the American Heart Association National Scientist Development Award (2012), the KSEA Young Investigator Award (2013), and the BMES-CMBE Rising Star Award (2013).

    Craig A. Simmons, University of Toronto
    Craig A. Simmons is a Professor at the University of Toronto with cross-appointments in the Department of Mechanical and Industrial Engineering and the Institute of Biomaterials and Biomedical Engineering. His research in cell mechanobiology, tissue engineering, and microtechnologies has been recognized with the Canada Research Chair in Mechanobiology, the McCharles Prize (2010), and the McLean Award (2012).

    Contributors

    Eddie Y. Chung, Qin Qin, Agamoni Bhattacharyya, Shaoying Lu, Yingxiao Wang, Niels Volkmann, Dorit Hanein, Yue Shao, Shinuo Weng, Jianping Fu, Christopher Moraes, Luke A. MacQueen, Yu Sun, Craig A. Simmons, Koichiro Uto, Elliot Fisher, Hong-Nam Kim, Chang Ho Seo, Deok-Ho Kim, Murat Guvendiren, Jason A. Burdick, Jiandong Wu, Francis Lin, Teresa Zulueta-Coarasa, Rodrigo Fernandez-Gonzalez, Ge Yang, Hao-Chih Lee, Yasaman Nematbakhsh, Chwee Teck Lim, Mitsuhiro Ebara, Andrew W. Holle, Jennifer L. Young, Yu Suk Choi, Chao Liu, Kevin Middleton, Lidan You, Vincent F. Fiore, Dwight M. Chambers, Thomas H. Barker, Andrea Leonard, Marita L. Rodriguez, Nathan J. Sniadecki, Hye Mi Kim, Junsang Doh, Yoojin Shin, Sewoon Han, Hyo-Eun Jeong, Jeong Ah Kim, Jessie S. Jeon, Sid Chung, Jerel Mueller, William Tyler

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