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Networks of Innovation
Vaccine Development at Merck, Sharp and Dohme, and Mulford, 1895–1995

$37.00 USD

Award Winner
Louis Galambos, Jane Eliot Sewell
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  • Date Published: February 2011
  • availability: This ISBN is for an eBook version which is distributed on our behalf by a third party.
  • format: Adobe eBook Reader
  • isbn: 9780511891144

$ 37.00 USD
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About the Authors
  • Networks of Innovation offers an historical perspective on the manner in which private-sector organizations have acquired, sustained, and periodically lost the ability to develop, manufacture, and market new serum antitoxins and vaccines. The primary focus is on the H. K. Mulford Company, on Sharp and Dohme, which acquired Mulford in 1929, and upon Merck & Co Inc., which merged with Sharp and Dohme in 1953. By surveying a century of innovation in biologicals, the authors are able to analyze the conditions that either promoted or prevented creative changes in this important industry. They show how the activities of these three commercial enterprises were related to a series of complex, evolving networks of scientific, governmental, and medical institutions in the United States and abroad. This is the first such history to draw exclusively on sources internal to Merck, one of the world's leading innovators in modern vaccines and pharmaceuticals.


    • Winner of the Thomas Newcomen Award for the best book in business history, 1995–1997

    Reviews & endorsements

    'The work is admirably referenced and will be of value to all who take an interest in the field of biologicals. It will repay careful reading by those involved in the management of innovation in the pharmaceutical industry.' John Hunt, The Pharmaceutical Journal

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    Product details

    • Date Published: February 2011
    • format: Adobe eBook Reader
    • isbn: 9780511891144
    • contains: 4 colour illus.
    • availability: This ISBN is for an eBook version which is distributed on our behalf by a third party.
  • Table of Contents

    1. 1894: 'The foremost medical question of the day'
    2. The Mulford story
    3. A Sharp & Dohme interlude
    4. The virology network and a new programme at Merck, Sharp & Dohme
    5. Hilleman's innovations: first phase, measles-mumps-rubella
    6. Dangerous interlude, Marek's Disease adjuvant 65, the Swine Flu drama
    7. Transforming bacteriology: a second phase, meningitis, pneumonia, haemophilus, influenzae
    8. New networks, new leadership: the Hepatitis B vaccines
    9. Vaccine innovation in the nineties: new strategies, new structures, and public confrontations
    A word about sources.

  • Author

    Louis Galambos, The Johns Hopkins University


    Jane Eliot Sewell


    Louis Galambos, Jane Eliot Sewell


    • Winner of the Thomas Newcomen Award for the best book in business history, 1995–1997

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