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Bacterial Adhesion to Host Tissues
Mechanisms and Consequences

$45.00 USD

Part of Advances in Molecular and Cellular Microbiology

T. J. Foster, Mumtaz Virji, Roderick McNab, Pauline S. Handley, Howard F. Jenkinson, Ian Blomfield, Clare Taylor, Ian Roberts, Janet R. Gilsdorf, Muhamed-Kheir Taha, Dorothy E. Pierson, Andreass U. Kresse, Frank Ebel, Carlos A. Guzman, Catharina Svanborg, G. Bergsten, H. Fisher, B. Freundéus, G. Godaly, E. Gustafsson, L. Hang, M. Hedlund, A-C. Lundstedt, M. Samuelsson, P. Samuelsson, M. Svensson, B. Wullt, Richard P. Ellen, Elizabeth L. Hartland, Gad Frankel, Stuart Knutton, Richard Lamont
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  • Date Published: December 2004
  • availability: This ISBN is for an eBook version which is distributed on our behalf by a third party.
  • format: Adobe eBook Reader
  • isbn: 9780511056987

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About the Authors
  • This book is about the adhesion of bacteria to their human hosts. Although adhesion is essential for maintaining members of the normal microflora in/on their host, it is also the crucial first stage in any infectious disease. It is important, therefore, to fully understand the mechanisms underlying bacterial adhesion so that we may be able to develop methods of maintaining our normal (protective) microflora, and of preventing pathogenic bacteria from initiating an infectious process. These topics are increasingly important because of the growing prevalence of antibiotic-resistant bacteria and, consequently, the need to develop alternative approaches for the prevention and treatment of infectious diseases. This book describes the bacterial structures responsible for adhesion and the molecular mechanisms underlying the adhesion process. It also deals with the consequences of adhesion for both the adherent bacterium and the host cell/tissue to which it has adhered.

    • Describes bacterial adhesion to host cells and tissue purely at the molecular level
    • Written by leading experts in the field to provide an overview of the topic
    • Uniquely, deals with the consequences of adhesion - both the effects on the bacteria and the effects on the host cell/tissue - as well as the mechanisms
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    Reviews & endorsements

    Review of the hardback: '… a compact source of information on the current state of the art in a selection of bacterial-host systems.' Roy Russell, Microbiology Today

    Review of the hardback: 'The authors are to be commended for this timely and important endeavour … certainly be of interest to a broad population of microbiologists and graduate students.' ASM News

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    Product details

    • Date Published: December 2004
    • format: Adobe eBook Reader
    • isbn: 9780511056987
    • availability: This ISBN is for an eBook version which is distributed on our behalf by a third party.
  • Table of Contents

    Part I. Bacterial Adhesins and Adhesive Structures:
    1. Surface protein adhesins of staphylococci T. J. Foster
    2. Mechanisms of utilisation of host signalling molecules by respiratory mucosal pathogens Mumtaz Virji
    3. Surface structures of oral streptococci involved in adhesion Roderick McNab, Pauline S. Handley and Howard F. Jenkinson
    4. Regulation and function of phase variation in Escherichia coli Ian Blomfield
    5. Regulation of capsule expression Clare Taylor and Ian Roberts
    6. Role of pili in Haemophilus influenzae adherence, colonization, and disease Janet R. Gilsdorf
    Part II. Effect of Adhesion on Bacterial Structure and Function:
    7. Transcriptional regulation of meningococcal gene expression upon adhesion to target cells Muhamed-Kheir Taha
    8. Induction of protein secretion by Yersinia enteroclitica through contact with eukaryotic cells Dorothy E. Pierson
    9. Functional modulation of pathogenic bacteria upon contact with host target cells Andreass U. Kresse, Frank Ebel and Carlos A. Guzman
    Part III. Consequences of Bacterial Adhesion for the Host:
    10. Adhesion, signal transduction and mucosal inflammation Catharina Svanborg et al.
    11. Adhesion of oral spirochaetes to host cells and its cytopathogenic consequences Richard P. Ellen
    12. Interactions between enteropathogenic Escherichia coli and epithelial cells Elizabeth L. Hartland, Gad Frankel and Stuart Knutton
    13. Host cell responses to Porphyromonas gingivalis and Actinobacillus actinomycetemcomitans Richard Lamont.

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    Bacterial Adhesion to Host Tissues

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  • Editor

    Michael Wilson, University College London

    Contributors

    T. J. Foster, Mumtaz Virji, Roderick McNab, Pauline S. Handley, Howard F. Jenkinson, Ian Blomfield, Clare Taylor, Ian Roberts, Janet R. Gilsdorf, Muhamed-Kheir Taha, Dorothy E. Pierson, Andreass U. Kresse, Frank Ebel, Carlos A. Guzman, Catharina Svanborg, G. Bergsten, H. Fisher, B. Freundéus, G. Godaly, E. Gustafsson, L. Hang, M. Hedlund, A-C. Lundstedt, M. Samuelsson, P. Samuelsson, M. Svensson, B. Wullt, Richard P. Ellen, Elizabeth L. Hartland, Gad Frankel, Stuart Knutton, Richard Lamont

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