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Molecular and Cellular Biophysics

£52.99

  • Date Published: January 2006
  • availability: Available
  • format: Paperback
  • isbn: 9780521624701

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  • Molecular and Cellular Biophysics provides advanced undergraduate and graduate students with a foundation in the basic concepts of biophysics. Students who have taken physical chemistry and calculus courses will find this book an accessible and valuable aid in learning how these concepts can be used in biological research. The text provides a rigorous treatment of the fundamental theories in biophysics and illustrates their application with examples. Conformational transitions of proteins are studied first using thermodynamics, and subsequently with kinetics. Allosteric theory is developed as the synthesis of conformational transitions and association reactions. Basic ideas of thermodynamics and kinetics are applied to topics such as protein folding, enzyme catalysis and ion channel permeation. These concepts are then used as the building blocks in a treatment of membrane excitability. Through these examples, students will gain an understanding of the general importance and broad applicability of biophysical principles to biological problems.

    • Offers a unique synthesis of concepts across a wide range of biophysical topics
    • Provides a rigorous theoretical treatment, alongside applications in biological systems
    • Author has been teaching biophysics for nearly 25 years
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    Reviews & endorsements

    '… would be a valuable addition to the library of any research lab at the physical end of biochemistry. … The language used in the book is extremely clear, and a mathematical approach is combined with clear links to real biochemistry …' Chemistry world

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    Product details

    • Date Published: January 2006
    • format: Paperback
    • isbn: 9780521624701
    • length: 528 pages
    • dimensions: 246 x 191 x 30 mm
    • weight: 0.91kg
    • contains: 206 b/w illus. 10 tables
    • availability: Available
  • Table of Contents

    Preface
    Acknowledgements
    1. Global transitions in proteins
    2. Molecular forces in biological structures
    3. Conformations of macromolecules
    4. Molecular associations
    5. Allosteric interactions
    6. Diffusion and Brownian motion
    7. Fundamental rate processes
    8. Association kinetics
    9. Multi-state kinetics
    10. Enzyme catalysis
    11. Ions and counter-ions
    12. Fluctuations
    13. Ion permeation and membrane potential
    14. Ion permeation and channel structure
    15. Cable theory
    16. Action potentials
    References
    Appendix 1. Expansions and series
    Appendix 2. Matrix algebra
    Appendix 3. Fourier analysis
    Appendix 4. Gaussian integrals
    Appendix 5. Hyperbolic functions
    Appendix 6. Polar and spherical coordinates.

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    Molecular and Cellular Biophysics

    Meyer B. Jackson

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  • Author

    Meyer B. Jackson, University of Wisconsin, Madison
    MEYER B. JACKSON is Professor of Physiology at the University of Wisconsin Medical School. He has been teaching graduate level biophysics for nearly 25 years.

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