Skip to content
Register Sign in Wishlist

Seasonal Patterns of Stress, Immune Function, and Disease


  • Date Published: October 2005
  • availability: Available
  • format: Paperback
  • isbn: 9780521021173

£ 27.99

Add to cart Add to wishlist

Other available formats:
Hardback, eBook

Looking for an inspection copy?

This title is not currently available on inspection

Product filter button
About the Authors
  • This book presents evidence that infection is cyclical with the seasons, and that this phenomenon is mirrored in cycles of immune function. The book identifies the mechanisms by which immune systems are bolstered to counteract seasonally-recurrent stressors, such as extreme temperature reductions and food shortages. Stress, infectious diseases, autoimmune diseases, and human cancers are examined, and the role of hormones such as melatonin and glucocorticoids is considered. The book begins with an overview of seasonality, biological rhythms and photoperiodism, and basic immunology, and then discusses seasonal fluctuations in disease prevalence, immune function, and energetics and endocrinology as they relate to immune function. The clinical significance of this issue is also addressed, as such seasonal changes may play an important role in the development and treatment of infections. This first monograph to examine seasonal immune function from an interdisciplinary perspective will serve practitioners as well as advanced undergraduates and graduate students in biology, immunology, human and veterinary medicine, neuroscience, endocrinology, and zoology.

    • Unique interdisciplinary perspective, will appeal to academic researchers and clinicians
    • Shows how an understanding of seasonal immune patterns may have real clinical implications in disease treatment and prevention
    • There are no other books which review the relationship between seasonal changes in immune function and disease
    Read more

    Reviews & endorsements

    ' … an interesting and rather provocative book. The issues explored in the book are wide-ranging and interdisciplinary, and will appeal to anyone interested in seasonality and health.' The Lancet

    '… valuable to anyone interested in immune function in wild animals, and also should be of interest to epidemiologists and immunologists attempting to understand patterns of disease prevalence.' L. Michael Romero, Tufts University

    See more reviews

    Customer reviews

    Not yet reviewed

    Be the first to review

    Review was not posted due to profanity


    , create a review

    (If you're not , sign out)

    Please enter the right captcha value
    Please enter a star rating.
    Your review must be a minimum of 12 words.

    How do you rate this item?


    Product details

    • Date Published: October 2005
    • format: Paperback
    • isbn: 9780521021173
    • length: 308 pages
    • dimensions: 229 x 151 x 18 mm
    • weight: 0.474kg
    • contains: 65 b/w illus. 13 tables
    • availability: Available
  • Table of Contents

    1. Seasonality
    2. Immune function
    3. Seasonal fluctuations in disease preference
    4. Seasonal changes in immune function
    5. Photoperiod, melatonin, and immunity
    6. Energetics and immune function
    7. Hormonal influence on immune function
    8. Clinical significance of seasonal patterns of immune function and disease

  • Authors

    Randy J. Nelson, Ohio State University

    Gregory E. Demas, Indiana University

    Sabra L. Klein, The Johns Hopkins University

    Lance J. Kriegsfeld, Columbia University, New York


    Frank Bronson

Sign In

Please sign in to access your account


Not already registered? Create an account now. ×

Sorry, this resource is locked

Please register or sign in to request access. If you are having problems accessing these resources please email

Register Sign in
Please note that this file is password protected. You will be asked to input your password on the next screen.

» Proceed

You are now leaving the Cambridge University Press website. Your eBook purchase and download will be completed by our partner Please see the permission section of the catalogue page for details of the print & copy limits on our eBooks.

Continue ×

Continue ×

Continue ×

Find content that relates to you

Join us online

This site uses cookies to improve your experience. Read more Close

Are you sure you want to delete your account?

This cannot be undone.


Thank you for your feedback which will help us improve our service.

If you requested a response, we will make sure to get back to you shortly.

Please fill in the required fields in your feedback submission.