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Textbook of Neural Repair and Rehabilitation

Volume 1. Neural Repair and Plasticity

2nd Edition

£128.00

  • Editors:
  • Michael Selzer, Shriners Hospitals Pediatric Research Center, Temple University School of Medicine
  • Stephanie Clarke, Department of Neurology, University Hospital, Lausanne
  • Leonardo Cohen, National Institute of Neurological Disorders and Stroke, Bethesda, Maryland
  • Gert Kwakkel, Department of Rehabilitation, VU University Medical Center, Amsterdam
  • Robert Miller, Case Western Reserve University, Ohio
Oswald Steward, Kimberly M. Christian, Andrew M. Poulos, Richard F. Thompson, Gavriel David, Ellen Barrett, Gareth Thomas, Richard L. Huganir, John H. Byrne, Diasinou Fioravante, Evangelos G. Antzoulatos, Jon H. Kaas, Hui-Xin Qi, Jonathan R. Wolpaw, Aiko K. Thompson, Randolph J. Nudo, Martin Munz, Edward S. Ruthazer, Kurt Haas, Josef P. Rauschecker, Krishnankutty Sathian, Melissa R. Andrews, Difei Wang, Chin Lik Tan, James W. Fawcett, Serge Rossignol, Brian J. Schmidt, Larry M. Jordan, S. Thomas Carmichael, Wenbin Deng, Frances E. Jensen, Anna-Katharine Brem, Jared C. Horvath, Alvaro Pascual-Leone, Agnes Floel, Leonardo G. Cohen, Thomas W. Gould, Carol Milligan, Erika Timar, Ahmet Höke, Jeffrey D. Macklis, Gerd Kempermann, Simon W. Moore, Timothy E. Kennedy, Matthew S. Kayser, Matthew B. Dalva, Jennifer Morgan, Michael Shifman, Binhai Zheng, Karim Fouad, Marco Domeniconi, Tim Spencer, Marie T. Filbin, Robert H. Miller, Himanshu Sharma, Bradley Lang, Jerry Silver, Charbel E.-H. Moussa, Vanessa S. Boyce, Joel M. Levine, Lorne M. Mendell, Toby A. Ferguson, Michael E. Selzer, Zhigang He, Joseph F. Bonner, Angelo C. Lepore, Mahendra S. Rao, Itzhak Fischer, Stephen G. Waxman, Young-Jin Son, Wesley J. Thompson, Jeffery D. Kocsis, Mary Bartlett Bunge, Christopher Trimby, George M. Smith, Michael S. Beattie, Jacqueline C. Bresnahan, Joseph J. Pancrazop, P. Hunter Peckham, Jeffrey R. Capadona, Paul D. Marasco, Chadwick B. Boulay, Beata Jarosiewicz, Leigh R. Hochberg, Lianhua Bai, Brandon Delia, Jordan Hecker, Robert H. Miller, Mindy F. Levin
View all contributors
  • Date Published: April 2014
  • availability: In stock
  • format: Hardback
  • isbn: 9781107011670

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About the Authors
  • In two freestanding volumes, the Textbook of Neural Repair and Rehabilitation provides comprehensive coverage of the science and practice of neurological rehabilitation. Revised throughout, bringing the book fully up to date, this volume, Neural Repair and Plasticity, covers the basic sciences relevant to recovery of function following injury to the nervous system, reviewing anatomical and physiological plasticity in the normal central nervous system, mechanisms of neuronal death, axonal regeneration, stem cell biology, and research strategies targeted at axon regeneration and neuron replacement. New chapters have been added covering pathophysiology and plasticity in cerebral palsy, stem cell therapies for brain disorders and neurotrophin repair of spinal cord damage, along with numerous others. Edited and written by leading international authorities, it is an essential resource for neuroscientists and provides a foundation for the work of clinical rehabilitation professionals.

    • Brings together the latest research in this rapidly developing field
    • Written and edited by world-renowned experts in the field
    • The first edition was a 'field-defining text'
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    Product details

    • Edition: 2nd Edition
    • Date Published: April 2014
    • format: Hardback
    • isbn: 9781107011670
    • length: 688 pages
    • dimensions: 283 x 223 x 35 mm
    • weight: 2.12kg
    • contains: 152 b/w illus. 59 colour illus. 13 tables
    • availability: In stock
  • Table of Contents

    Part I. Neural Plasticity – Cellular and Molecular Mechanisms of Neural Plasticity:
    1. Degenerative changes and reactive growth responses of neurons following denervation and axotomy: historical concepts and their modern embodiments
    2. Learning and memory: basic principles and model systems
    3. Short-term plasticity: facilitation, augmentation, potentiation and depression
    4. Long-term potentiation and long-term depression
    5. Cellular and molecular mechanisms of associative and nonassociative learning
    Part II. Functional Plasticity in the Central Nervous System:
    6. Plasticity of mature and developing somatosensory systems
    7. Activity-dependent plasticity in the intact spinal cord
    8. Plasticity of cerebral motor functions: implications for repair and rehabilitation
    9. Plasticity in visual connections: retinal ganglion cell axonal development and regeneration
    10. Plasticity in auditory functions
    11. Cross-modal plasticity in the visual system
    Part III. Plasticity after Injury to the Central Nervous System:
    12. The role of extracellular matrix in plasticity in the spinal cord
    13. Spinal plasticity underlying the recovery of locomotion after injury
    14. Cellular mechanisms of plasticity after brain lesions
    15. Pathophysiology and plasticity in cerebral palsy
    16. Noninvasive brain stimulation in cognitive rehabilitation: guiding plasticity after injury to the central nervous system
    17. From bench to bedside: influence of theories of plasticity on human neurorehabilitation
    Part IV. Neural Repair – Basic Cellular and Molecular Processes:
    18. Neuronal death and rescue: neurotrophic factors and anti-apoptotic mechanisms
    19. Axon degeneration and rescue
    20. Adult neurogenesis and neural precursors, progenitors, and stem cells in the adult central nervous system
    21. Axon guidance during development and regeneration
    22. Synaptogenesis
    Part V. Determinants of Regeneration in the Injured Nervous System:
    23. Non-mammalian models of nerve regeneration
    24. Myelin-associated axon growth inhibitors
    25. Inhibitors of axonal regeneration
    26. Glial development and their role in axon regeneration
    27. Effects of the glial scar and extracellular matrix molecules on axon regeneration
    28. The role of the inflammatory response in central nervous system injury and regeneration
    29. Neurotrophin repair of spinal cord damage
    30. Intraneuronal determinants of regeneration
    Part VI. Promotion of Regeneration in the Injured Nervous System:
    31. Cellular replacement in spinal cord injury
    32. Dysfunction and recovery in demyelinated and dysmyelinated axons
    33. Role of Schwann cells in peripheral nerve regeneration
    34. Transplantation of Schwann cells and olfactory ensheathing cells as a therapeutic strategy in spinal cord injury
    35. Trophic factor delivery by gene therapy
    36. Assessment of sensorimotor function after experimental spinal cord injury and repair
    Part VII. Translational Research: Application to Human Neural Injury:
    37. Biomimetic design of neural prostheses
    38. Brain responses to neural prostheses
    39. Brain-computer interfaces
    40. Intracranial brain-computer interfaces for communication and control
    41. Stem cell therapies for brain disorders
    42. Understanding motor recovery and compensation in neurorehabilitation
    Index.

  • Editors

    Michael Selzer, Shriners Hospitals Pediatric Research Center, Temple University School of Medicine
    Michael Selzer is Director and Professor, Department of Neurology at Shriners Hospitals Pediatric Research Center, Temple University School of Medicine, Philadelphia, PA, USA.

    Stephanie Clarke, Department of Neurology, University Hospital, Lausanne
    Stephanie Clarke is Professor, Service de Neuropsychologie et de Neuroréhabilitation, Centre Hospitalier Universitaire Vaudois, Université de Lausanne, Switzerland.

    Leonardo Cohen, National Institute of Neurological Disorders and Stroke, Bethesda, Maryland
    Leonardo Cohen is Professor, Human Cortical Physiology Section and Stroke Neurorehabilitation Section, National Institutes of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA.

    Gert Kwakkel, Department of Rehabilitation, VU University Medical Center, Amsterdam
    Gert Kwakkel is Professor of Rehabilitation Medicine, Move Research Institute, VU University Medical Center (VUmc), Amsterdam; Centre of Excellence for Rehabilitation Medicine, Rehabilitation Centre 'De Hoogstraat' and Department of Rehabilitation and Sports Medicine, Rudolf Magnus Institute of Neuroscience, UMC Utrecht, Utrecht, The Netherlands.

    Robert Miller, Case Western Reserve University, Ohio
    Robert Miller is Vice Dean for Research, Department of Neuroscience, Center for Translational Neuroscience, Case Western Reserve University, Cleveland, OH, USA.

    Contributors

    Oswald Steward, Kimberly M. Christian, Andrew M. Poulos, Richard F. Thompson, Gavriel David, Ellen Barrett, Gareth Thomas, Richard L. Huganir, John H. Byrne, Diasinou Fioravante, Evangelos G. Antzoulatos, Jon H. Kaas, Hui-Xin Qi, Jonathan R. Wolpaw, Aiko K. Thompson, Randolph J. Nudo, Martin Munz, Edward S. Ruthazer, Kurt Haas, Josef P. Rauschecker, Krishnankutty Sathian, Melissa R. Andrews, Difei Wang, Chin Lik Tan, James W. Fawcett, Serge Rossignol, Brian J. Schmidt, Larry M. Jordan, S. Thomas Carmichael, Wenbin Deng, Frances E. Jensen, Anna-Katharine Brem, Jared C. Horvath, Alvaro Pascual-Leone, Agnes Floel, Leonardo G. Cohen, Thomas W. Gould, Carol Milligan, Erika Timar, Ahmet Höke, Jeffrey D. Macklis, Gerd Kempermann, Simon W. Moore, Timothy E. Kennedy, Matthew S. Kayser, Matthew B. Dalva, Jennifer Morgan, Michael Shifman, Binhai Zheng, Karim Fouad, Marco Domeniconi, Tim Spencer, Marie T. Filbin, Robert H. Miller, Himanshu Sharma, Bradley Lang, Jerry Silver, Charbel E.-H. Moussa, Vanessa S. Boyce, Joel M. Levine, Lorne M. Mendell, Toby A. Ferguson, Michael E. Selzer, Zhigang He, Joseph F. Bonner, Angelo C. Lepore, Mahendra S. Rao, Itzhak Fischer, Stephen G. Waxman, Young-Jin Son, Wesley J. Thompson, Jeffery D. Kocsis, Mary Bartlett Bunge, Christopher Trimby, George M. Smith, Michael S. Beattie, Jacqueline C. Bresnahan, Joseph J. Pancrazop, P. Hunter Peckham, Jeffrey R. Capadona, Paul D. Marasco, Chadwick B. Boulay, Beata Jarosiewicz, Leigh R. Hochberg, Lianhua Bai, Brandon Delia, Jordan Hecker, Robert H. Miller, Mindy F. Levin

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