Skip to content
Register Sign in Wishlist

Neuropathology of Neurodegenerative Diseases
A Practical Guide
Book and Online

Out of Print

Gabor G. Kovacs, Erin C. Golden, Keith A. Josephs, Walter Pirker, James W. Ironside, Isidro Ferrer, Charles Duyckaerts, Irina Alafuzoff, Maria Pikkarainen, Laura Parkkinen, Diane L. Ritchie, Alexander H. Peden, Mark W. Head, Natacha Joyon, Alexandra Durr, Tibor Hortobágyi, Nigel J. Cairns, Ruben Vidal, Bernardino Ghetti
View all contributors
  • Date Published: December 2014
  • availability: Unavailable - out of print May 2017
  • format: Mixed media product
  • isbn: 9781107442429

Out of Print
Mixed media product

Unavailable - out of print May 2017
Unavailable Add to wishlist

Other available formats:

Looking for an inspection copy?

This title is not currently available on inspection

Product filter button
About the Authors
  • This practical guide to the diagnosis of neurodegenerative diseases discusses modern molecular techniques, morphological classification, fundamentals of clinical symptomology, diagnostic pitfalls and immunostaining protocols. It is based on the proteinopathy concept of neurodegenerative disease, which has influenced classification and provides new strategies for therapy. Numerous high-quality images, including histopathology photomicrographs and neuroradiology scans, accompany the description of morphologic alterations and interpretation of immunoreactivities. Diagnostic methods and criteria are placed within recent developments in neuropathology, including the now widespread application of immunohistochemistry. To aid daily practice, the guide includes diagnostic algorithms and offers personal insights from experienced experts in the field. Special focus is given to the way brain tissue should be handled during diagnosis. This is a must-have reference for medical specialists and specialist medical trainees in the fields of pathology, neuropathology and neurology working with neuropathologic features of neurodegenerative diseases. The book is packaged with a password, giving the user online access to all the text and images.

    • Written in accessible language, avoiding the use of overlapping and complicated nomenclature
    • Includes sampling and staining strategies and molecular methodological approaches, orientating the reader in the laboratory techniques used in the diagnosis of neurodegenerative diseases
    • Describes molecular pathologic features of neurodegenerative disease, enabling classification on a microscopic level
    Read more

    Reviews & endorsements

    'Neuropathology of Neurodegenerative Diseases: A Practical Guide edited by Gabor G. Kovacs is a highly recommended book, written from the perspective of both neuropathologist and clinician. This practical guide is comprehensively updated with the most recent morphological and genetic advancements in the differential diagnoses of neurodegenerative diseases. The supreme author team introduces the core concept of neurodegenerative disorders and guides the reader systematically from the basic practical approach in sampling of brain tissue, histological staining, and molecular methods toward clinical-pathological description of specific proteinopathy. With its extensive combination of masterfully edited text, easy-to-read tables, graphs and high-quality illustrations, this practical guide makes learning and reading of neurodegenerative disorders easy and enjoyable.' Nenad Bogdanovic, Universitet i Oslo and Karolinska Institutet, Stockholm

    'The book is highly readable, provides a large amount of information as well as diagnostic clues on the various disorders. I can highly recommend the book. It should belong on the bookshelf of each diagnostic neuropathologist.' Serge Weis, Clinical Neuropathology

    'Lots of  full-color images abound in this treasure of a book. This is really a must-have resource in the rapidly-growing field of study on neurologic disease.' Nano Khilnani, Biz India

    'This is an excellent book, produced by a group of highly regarded experts in the field, masterfully edited by Gabor Kovacs. The text is clear, authoritative, accurate and up to date. The way the book is set out allows it to be used as a 'bench guide' to classification and I recommend it highly to any neuropathologist involved in the laboratory diagnosis of neurodegenerative disease.' Ian S. Scott, The Bulletin

    See more reviews

    Customer reviews

    Not yet reviewed

    Be the first to review

    Review was not posted due to profanity


    , create a review

    (If you're not , sign out)

    Please enter the right captcha value
    Please enter a star rating.
    Your review must be a minimum of 12 words.

    How do you rate this item?


    Product details

    • Date Published: December 2014
    • format: Mixed media product
    • isbn: 9781107442429
    • length: 316 pages
    • dimensions: 246 x 189 x 14 mm
    • weight: 0.88kg
    • contains: 14 b/w illus. 136 colour illus. 50 tables
    • availability: Unavailable - out of print May 2017
  • Table of Contents

    List of contributors
    1. Introduction: classification of neurodegenerative diseases Gabor G. Kovacs
    2. Clinical aspects of dementia Erin C. Golden and Keith A. Josephs
    3. Clinical aspects of movement disorders Walter Pirker
    4. Ethical, health and safety considerations James W. Ironside
    5. Practical approach to diagnosis: sampling and basic stainings Gabor G. Kovacs
    6. Molecular methods Isidro Ferrer
    7. Alzheimer's disease Charles Duyckaerts
    8. Tauopathies Gabor G. Kovacs
    9. Synucleinopathies Irina Alafuzoff, Maria Pikkarainen and Laura Parkkinen
    10. Human prion diseases James W. Ironside, Diane L. Ritchie, Alexander H. Peden and Mark W. Head
    11. Neurodegenerative diseases linked to trinucleotide repeats Charles Duyckaerts, Natacha Joyon and Alexandra Durr
    12. Amyotrophic lateral sclerosis and frontotemporal lobar degeneration Tibor Hortobágyi and Nigel J. Cairns
    13. Other NDG conditions I: hereditary cerebral amyoid angiopathies Ruben Vidal and Bernardino Ghetti
    14. Other NDG conditions II: familial encephalopathy with neuroserpin inclusion bodies Ruben Vidal and Bernardino Ghetti
    15. Other NDG conditions III: hereditary ferritinopathies Ruben Vidal and Bernardino Ghetti
    16. Other NDG conditions IV: neurodegeneration with brain iron accumulation Isidro Ferrer
    17. Concomitant pathologies I: cerebrovascular diseases Isidro Ferrer
    18. Concomitant pathologies II: neurodegenerative conditions Gabor G. Kovacs, Isidro Ferrer and Irina Alafuzoff
    Appendix A. Molecular classification of frontotemporal lobar degeneration (FTLD) with genetic correlations Gabor G. Kovacs and Nigel J. Cairns
    Appendix B. Scheme for evaluation of frontotemporal lobar degeneration (FTLD) Gabor G. Kovacs and Nigel J. Cairns

  • Editor

    Gabor G. Kovacs, Medical University of Vienna, Austria
    Gabor G. Kovacs is an Associate Professor at the Institute of Neurology in Vienna, Austria.


    Gabor G. Kovacs, Erin C. Golden, Keith A. Josephs, Walter Pirker, James W. Ironside, Isidro Ferrer, Charles Duyckaerts, Irina Alafuzoff, Maria Pikkarainen, Laura Parkkinen, Diane L. Ritchie, Alexander H. Peden, Mark W. Head, Natacha Joyon, Alexandra Durr, Tibor Hortobágyi, Nigel J. Cairns, Ruben Vidal, Bernardino Ghetti

Sign In

Please sign in to access your account


Not already registered? Create an account now. ×

Sorry, this resource is locked

Please register or sign in to request access. If you are having problems accessing these resources please email

Register Sign in
Please note that this file is password protected. You will be asked to input your password on the next screen.

» Proceed

You are now leaving the Cambridge University Press website. Your eBook purchase and download will be completed by our partner Please see the permission section of the catalogue page for details of the print & copy limits on our eBooks.

Continue ×

Continue ×

Continue ×

Find content that relates to you

Join us online

This site uses cookies to improve your experience. Read more Close

Are you sure you want to delete your account?

This cannot be undone.


Thank you for your feedback which will help us improve our service.

If you requested a response, we will make sure to get back to you shortly.

Please fill in the required fields in your feedback submission.