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Biomechanics and Cells

$54.00 USD

Part of Society for Experimental Biology Seminar Series

  • Date Published: February 2011
  • availability: This ISBN is for an eBook version which is distributed on our behalf by a third party.
  • format: Adobe eBook Reader
  • isbn: 9780511884740

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About the Authors
  • Although the effects of exercise and mechanical forces on musculoskeletal and cardiovascular systems have been well documented, the actual mechanisms by which mechanical forces act at the cellular level are not well understood. At present, studies of the interaction of mechanical forces with cells encompass many different cell types in various tissues. This volume draws together these apparently disparate observations and makes comparisons between the nature of cellular responses in different tissues. Studies of cells derived from skeletal muscle, bone and cardiovascular tissue are considered to provide a comprehensive synthesis and review of recent work. The volume will be of interest to all those working in musculoskeletal and cardiovascular biology, as well as those taking courses in exercise and sport science, biomechanics and orthopaedics.

    • The first book to compare and synthesise the results of a range of apparently disparate studies on mechanical interactions with cells
    • Considers the effect of various forces on a range of different tissue types
    • Presents a unique cellular approach to the understanding of biomechanics
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    Product details

    • Date Published: February 2011
    • format: Adobe eBook Reader
    • isbn: 9780511884740
    • contains: 75 b/w illus. 5 tables
    • availability: This ISBN is for an eBook version which is distributed on our behalf by a third party.
  • Table of Contents

    Part I. Soft Tissue:
    1. Signal transduction in vascular cells exposed to cyclic strain
    2. Effects of pressure overload on vascular smooth muscle cells
    3. Effect of increased flow on release of vasoactive substances from vascular endothelial cells
    4. Modulation of endothelium derived relaxing factor activity by flow
    5. Stretch, overload and gene expression in muscle
    6. Stretch sensitivity in stretch receptor muscles
    7. Mechanical interactions with plant cells - a selective overview
    8. Mechanical tensing of cells and chromosome arrangement
    9. Alterations in gene expression induced by low-frequency, low-intensity electromagnetic fields
    Part II. Hard Tissue:
    10. Cellular modelling of mechanical interactions with the skeleton
    11. Mechanical and hormonal influences in vivo cause regional differences in bone remodelling
    12. Mechanically sensitive cells in bone
    13. Mechanical stress and bone development
    14. Applications of homogenous, defined strains to cell cultures
    15. The role of prostaglandin in bone cells as mediators of mechanical strain
    16. Effects of mechanical stretch on actin polymerisation in fibroblasts of the periodontium
    17. Modulation of cartilage extracellular matrix turnover by pulsed electromagnetic fields

  • Editors

    Fiona Lyall, University of Glasgow

    A. J. El Haj, University of Birmingham

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