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Bacterial Evasion of Host Immune Responses

$131.00 USD

Part of Advances in Molecular and Cellular Microbiology

Benjamin M. Chain, Janusz Marcinkiewicz, Kayvan R. Niazi, Steven A. Porcelli, Robert L. Modlin, Richard Bellamy, Michael A. Kerr, Brian Henderson, Mogens Kilian, Nigel J. Saunders, Ake Forsberg, Roland Rosqvist, Maria Fallman, John Fraser, Thomas Proft, Vickery Arcus, Edward Baker, David Pritchard, Doreen Hooi, Eleanor Watson, Sek Chow, Gary Telford, Barrie Bycroft, Siri Ram Chhabra, Christopher Harty, Miguel Camara, Stephen Diggle, Paul Williams, Rob M. Seymour, Jan-Michael Klapproth, Michael S. Donnenberg, Klaus Ruckdeschel, Bruno Rouot, Jurgen Heesemann
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  • Date Published: December 2004
  • availability: This ISBN is for an eBook version which is distributed on our behalf by a third party.
  • format: Adobe eBook Reader
  • isbn: 9780511057052

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  • Our survival as multicellular organisms requires the constant surveillance of our internal and external (mucosal) environments by the multifarious elements of the innate and acquired systems of immunity. The objective of this surveillance, expensive as it is to the organisms, is to recognise and kill invading microorganisms. Over the past fifty years the cells and mediators involved in our immune defences have been painstakingly identified. However, it is only relatively recently that the ability of microorganisms to evade immunity has been recognised and investigated. Bacterial Evasion of Host Immune Responses introduces the reader to the mechanisms used by bacteria to evade both humoral and cellular immune responses, using systems ranging in complexity from the simple quorum sensing molecules - acyl homoserine lactones - to the supramolecular syringe-like devices of type III secretion systems. This book will be of interest to researchers and graduate students in microbiology, immunology, pharmacology and molecular medicine.

    •  First book to focus on bacterial evasion of immunity
    •  Written by leading experts in the field, providing an up-to-the-minute overview of the topic
    •  Covers immune recognition of bacteria, as well as bacterial evasion of the immune system
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    Product details

    • Date Published: December 2004
    • format: Adobe eBook Reader
    • isbn: 9780511057052
    • contains: 24 b/w illus. 9 colour illus. 12 tables
    • availability: This ISBN is for an eBook version which is distributed on our behalf by a third party.
  • Table of Contents

    Preface
    Part I. Recognition of Bacteria:
    1. The dendritic cell in bacterial infection: sentinel or Trojan horse? Benjamin M. Chain
    2. CD1 and non-peptide recognition systems in microbial immunity Kayvan R. Niazi, Steven A. Porcelli and Robert L. Modlin
    3. The NRAMP family: co-evolution of a host/pathogen defence system Richard Bellamy
    Part II. Evasion of Humoral Immunity:
    4. Evasion of complement pathways by bacteria Michael A. Kerr and Brian Henderson
    5. Bacterial immunoglobulin-evading mechanisms: Ig degradation and Ig-binding proteins Mogens Killian
    6. Evasion of antibody responses: bacterial phase variation Nigel J. Saunders
    Part III. Evasion of Cellular Immunity:
    7. Type III protein secretion and resistance to phagocytosis Ake Forsberg, Roland Rosqvist and Maria Fallman
    8. Bacterial superantigens and immune evasion John Fraser, Thomas Proft, Vickery Arcus and Edward Baker
    9. Density-dependent bacterial signalling molecules as immune modulators David Pritchard, Doreen Hooi, Eleanor Watson, Sek Chow, Gary Telford, Barrie Bycroft, Siri Ram Chhabra, Christopher Harty, Miguel Camara, Stephen Diggle and Paul Williams
    10. Microbial modulation of cytokine networks B. Henderson and Rob M. Seymour
    11. Enterotoxins: adjuvants and immune inhibitors Jan-Michael Klapproth and Michael S. Donnenberg
    12. Type III protein secretion and inhibition of NF-κB Klaus Ruckdeschel, Bruno Rouot and Jürgen Heesemann.

  • Editors

    Brian Henderson, University College London

    Petra C. F. Oyston, Defence Science and Technology Laboratory, Salisbury

    Contributors

    Benjamin M. Chain, Janusz Marcinkiewicz, Kayvan R. Niazi, Steven A. Porcelli, Robert L. Modlin, Richard Bellamy, Michael A. Kerr, Brian Henderson, Mogens Kilian, Nigel J. Saunders, Ake Forsberg, Roland Rosqvist, Maria Fallman, John Fraser, Thomas Proft, Vickery Arcus, Edward Baker, David Pritchard, Doreen Hooi, Eleanor Watson, Sek Chow, Gary Telford, Barrie Bycroft, Siri Ram Chhabra, Christopher Harty, Miguel Camara, Stephen Diggle, Paul Williams, Rob M. Seymour, Jan-Michael Klapproth, Michael S. Donnenberg, Klaus Ruckdeschel, Bruno Rouot, Jurgen Heesemann

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