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The Osteoporosis Primer

$122.00 USD

Janet E. Henderson, David Goltzman, A. Robin Poole, Sheila Laverty, Fackson Mwale, Jane E. Aubin, Johan Heersche, Morris F. Manolson, Marc D. McKee, Jaro Sodek, Lawrence J. Fraher, Patricia H. Watson, Geoffrey N. Hendy, Marielle Gascon-Barre, Harriet S. Tenenhouse, Milan S. Patel, Laurence A. Rubin, David E. C. Cole, Velimir Matkovic, John D. Landoll, Heather A. McKay, Karim M. Khan, Frank Rauch, Francis H. Glorieux, Karen Prestwood, Lawrence G. Raisz, Pierre D'Amour, Patrick M. Doran, Sundeep Khosla, Jaques Brown, David Hanley, Jaqueline C. Hodge, Paul D. Miller, Carol Zapalowski, Jonathan D. Adachi, Alexandra Papaioannou, Felicia Cosman, Robert Lindsay, Fred Singer, Payam Minoofar, Marc D. Grynpas, D. Chachra, H. Limeback, Anthony B. Hodsman, Richard Kremer
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  • Date Published: January 2005
  • availability: This ISBN is for an eBook version which is distributed on our behalf by a third party.
  • format: Adobe eBook Reader
  • isbn: 9780511036750

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About the Authors
  • Osteoporosis is one of the leading causes of morbidity and mortality amongst the elderly. The rationale for The Osteoporosis Primer is to provide an introductory text that relates the clinical presentation of osteoporosis to its molecular biochemical basis. The text has been organised into four sections that deal with the molecular/cellular components of bone, the development of peak bone mass, the pathophysiology of aging bone and, finally, how all of these relate to the prevention, diagnosis and treatment of osteoporosis. The international team of authors includes many leading clinicians and scientists who have provided the reader with a concise, yet comprehensive, synopsis of bone development and skeletal homeostasis. This will be an essential introduction for individuals working on osteoporosis including students and doctors considering a career related to metabolic bone disease, physicians in general practice, geriatricians, rheumatologists, and endocrinologists.

    • International team of authors includes many leading clinicians and scientists
    • Presents cutting edge knowledge in bone cell biology in the context of clinical practice
    • An essential introduction for individuals working on metabolic disease and for medical and graduate students
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    Reviews & endorsements

    'I really enjoyed tying together the cell biology and the basis of the current treatments and potential therapeutic interventions. I found that I knew a lot more about bone cell physiology, bone turnover and cell signalling by the end of the section. … The book succeeds as an introductory text on metabolic bone disease and provides insight into the complexity of the subject without becoming overwhelming.' Gerontology

    'A clearly written and updated text … on a topic of increasing interest.' Journal of Pediatric Endocrinology and Metabolism

    'This is a concise yet comprehensive synopsis of bone developments and skeletal homeostasis.' Aslib Book Guide

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    Product details

    • Date Published: January 2005
    • format: Adobe eBook Reader
    • isbn: 9780511036750
    • contains: 50 b/w illus. 12 tables
    • availability: This ISBN is for an eBook version which is distributed on our behalf by a third party.
  • Table of Contents

    Preface Janet E. Henderson and David Goltzman
    Part I. Molecular and Cellular Environment of Bone:
    1. Endochondral bone formation and development in the axial and appendicular skeletaon A. Robin Poole, Sheila Laverty and Fackson Mwale
    2. The role of osteoblasts Jane E. Aubin
    3. Osteoclasts: characteristics and regulation of formation and activity Johan Heersche and Morris F. Manolson
    4. Bone matrix proteins Marc D. McKee and Jaro Sodek
    5. Local regulators of bone turnover Lawrence J. Fraher and Patricia H. Watson
    6. The PTH/PTHrP system and calcium homeostasis Geoffrey N. Hendy
    7. Vitamin D metabolism Marielle Gascon-Barre
    8. Sodium-dependent phosphate transport in kidney, bone and intestine Harriet S. Tenenhouse
    Part II. Determinants of Peak Bone Mass:
    9. Molecular genetic analysis of growth factor signalling in bone Janet E. Henderson and David Goltzman
    10. Genetic determinants of osteoporosis Milan S. Patel, Laurence A. Rubin and David E. C. Cole
    11. Non-genetic determinants of peak bone mass Velimir Matkovic and John D. Landoll
    12. Bone mineral acquisition during childhood and adolescence: physical exercise as a preventative measure Heather A. McKay and Karim M. Khan
    13. Osteoporosis in children Frank Rauch and Francis H. Glorieux
    Part III. Pathophysiology of the Aging Skeleton:
    14. Consequences of alterations in bone remodeling Karen Prestwood and Lawrence G. Raisz
    15. The role of parathyroid hormone and hyperparathyroidism in osteoporosis Pierre D'Amour
    16. Senile osteoporosis Patrick M. Doran and Sundeep Khosla
    Part IV. Clinical Aspects of Osteoporosis
    17. Epidemiology Jaques Brown
    18. Biochemical markers of bone turnover David Hanley
    19. Radiologic assessment of osteoporosis Jaqueline C. Hodge
    20. Bone mineral density measurements Paul D. Miller and Carol Zapalowski
    21. Hormone replacement therapy Jonathan D. Adachi and Alexandra Papaioannou
    22. Selective estrogen receptor modulators Felicia Cosman and Robert Lindsay
    23. Bisphosphonate therapy of osteoporosis Fred Singer and Payam Minoofar
    24. The action of fluoride on bone Marc D. Grynpas, D. Chachra and H. Limeback
    25. PTH peptides as anabolic agents in bone Anthony B. Hodsman
    26. Vitamin D and Vitamin D analogs as therapeutic agents Richard Kremer.

  • Editors

    Janet E. Henderson, McGill University, Montréal

    David Goltzman, McGill University, Montréal

    Contributors

    Janet E. Henderson, David Goltzman, A. Robin Poole, Sheila Laverty, Fackson Mwale, Jane E. Aubin, Johan Heersche, Morris F. Manolson, Marc D. McKee, Jaro Sodek, Lawrence J. Fraher, Patricia H. Watson, Geoffrey N. Hendy, Marielle Gascon-Barre, Harriet S. Tenenhouse, Milan S. Patel, Laurence A. Rubin, David E. C. Cole, Velimir Matkovic, John D. Landoll, Heather A. McKay, Karim M. Khan, Frank Rauch, Francis H. Glorieux, Karen Prestwood, Lawrence G. Raisz, Pierre D'Amour, Patrick M. Doran, Sundeep Khosla, Jaques Brown, David Hanley, Jaqueline C. Hodge, Paul D. Miller, Carol Zapalowski, Jonathan D. Adachi, Alexandra Papaioannou, Felicia Cosman, Robert Lindsay, Fred Singer, Payam Minoofar, Marc D. Grynpas, D. Chachra, H. Limeback, Anthony B. Hodsman, Richard Kremer

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